Your Career at OncoOne

Diverse expertise, shared ambition.

As exemplified by our Company name, OncoOne operates under our united ambition to access the varied potential of oxMIF to provide innovative treatments for patients living with cancer and autoimmune diseases. Interested in contributing to our cause? Join the OncoOne team!

Principal Scientist / Manager R&D (all genders) – Cancer Biology

Working hours: Full-time (40h/week)
Location: VBC, Karl Farkas-Gasse 22, 1030 Vienna
Job level: Professionally experienced
Functional area: Research & Development

OncoOne is a biotech start-up dedicated to developing innovative therapeutics to treat patients with solid tumors and inflammatory diseases. We are currently looking for a highly motivated and team-orientated Principal Scientist/Manager to support the development of novel therapeutics within the Internal Research Group at our laboratories at Karl-Farkas-Gasse 22, 1030 Vienna.

Duties and Responsibilities:

  • Lead translational research for cancer immunotherapy programs.
  • Provide in vivo pharmacology expertise during the discovery and development phases of antibody-based drug discovery programs.
  • Manage external research relationships with academic and commercial partners including in vivo, in vitro and ex vivo research that enable interrogation of pharmacodynamic, mechanisms of action, diagnostic hypotheses, and mechanisms of resistance/drug synergy.
  • Set up clinical biomarker strategies for antibody-based drug candidates.
  • Manage direct or indirect reports, including Scientists and Associate Scientists.
  • Authoring documents to support regulatory filings, patent applications and manuscripts published in peer-reviewed journals.

Required Qualifications:

  • A PhD with post-doctoral training or equivalent experience in immunology, oncology, cell biology, or a related field is required.
  • Ideal candidates have a minimum of 5 years of research experience in cancer biology or immuno-oncology.
  • High level of production in either an industrial or academic setting, as evidenced by publications, presentations at international conferences, patents, and/or direct involvement of advancing molecules into clinical development.
  • Strong experience in tumor models (in vitro, in vivo and ex vivo), assessment of therapeutic responses using a diverse array of pharmacodynamics assays, high content biomarker assessments, and experience in translational immunology.
  • Detailed expertise in innate and adaptive immune mechanisms and a high level of understanding of basic oncogenic drivers and the interplay between tumors and the immune system.
  • High level of scientific curiosity, good communication skills, good managerial qualities, and a strong dedication to translating basic research.
  • Excellent communication and presentation skills.
  • Self-motivated, open-minded, and innovative team player with good problem-solving capabilities

Our Offer:

  • OncoOne is an equal opportunity employer that maintains a diverse and inclusive work culture.
  • International work environment
  • Perks: Free coffee and tea in the office
    Meal allowance up to € 5,00 for each working day
  • Modern office space in a central location at the Vienna BioCenter (1030 Vienna) with a good connection to public transportation

We offer a salary in line with the current job market and based on professional and personal skills and experiences. For this full-time position we offer at least an annual gross salary of EUR 75.000,-. The actual remuneration package will be based on your professional experience, qualification, and skills.


If you are interested in the position, please send your application (cover letter and CV) to:

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We look forward to receiving your application!