OncoOne Assembles a Team With the Perfect Blend of Experience, Precisely When It’s Needed
The leadership team at OncoOne comprises seasoned professionals with decades of collective expertise spanning all phases of discovery and development. Their extensive R&D expertise, coupled with firsthand experience guiding novel therapies successfully through regulatory pathways, paves the way for precision medicines aimed at effectively improving patient outcomes and quality of life.
Leadership Team
Randolf Kerschbaumer, PhD
Co-Founder & Chief Executive Officer
Randolf Kerschbaumer, PhD
Co-Founder & Chief Executive Officer
Dr. Randolf Kerschbaumer, CEO and Co-Founder of OncoOne, brings over 25 years of experience from academia and big pharma R&D to the company. His comprehensive understanding of the drug development process, from early screening through to clinical trials, has been pivotal in shaping OncoOne's success. Under his leadership, OncoOne has expanded its reach globally and established a subsidiary in the USA. Randolf's intellectual curiosity, passion for science, and entrepreneurial drive allow him to effectively merge scientific innovation with strategic business planning. Before founding OncoOne, Randolf held several senior-level positions in R&D, focusing on therapeutics for cancer, inflammation, and hematologic disorders. He started his professional career at Baxter BioScience, progressing to senior leadership roles such as Head of Antibody Technology at Baxalta and Head of Oncology Research at Shire. His work has significantly contributed to the discovery and progression of antibody-based drug modalities with therapeutic potential from concept to Phase II clinical studies. Randolf earned his PhD in Biotechnology from the Vienna University of Natural Resources and Life Sciences (BOKU).
Michael Thiele, PhD
Co-Founder & Chief Scientific Officer
Michael Thiele, PhD
Co-Founder & Chief Scientific Officer
Michael, Co-Founder and Chief Scientific Officer (CSO) at OncoOne, has over two decades of expertise in immunology, tumor biology, biomarker discovery, and the development of biologics. As the CSO, he leads the company's strategic direction and drives the innovative PreTarg-it® platform, which aims for targeted delivery of therapies directly to tumor sites. Michael's profound knowledge of cell biology and his extensive global scientific connections enable him to establish and maintain strong partnerships with top experts in the field. Before establishing OncoOne, he led the Department of Cell Biology in Oncology Research at Shire. Earlier in his career, Michael held progressively senior roles at Baxter BioScience and its successor, Baxalta, collaborating with leading academics and industry leaders. Michael's significant contributions to medical science include recognizing oxMIF as a key therapeutic target, which marks a crucial advance in the creation of new therapies for autoimmune and chronic inflammatory conditions. Michael has been instrumental in advancing the first-generation anti-oxMIF antibody, imalumab, from early-stage research to phase II clinical trials. He obtained his PhD in Biology from the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, where he investigated tumor-promoting and pro-inflammatory properties of MIF.
Alexander Schinagl, PhD
Co-Founder & Chief Technology Officer
Alexander Schinagl, PhD
Co-Founder & Chief Technology Officer
Alexander Schinagl, Co-Founder and Chief Technology Officer at OncoOne, plays a pivotal role in the company's antibody design and engineering programs. In addition, he provides IP counsel to ensure robust patent protection. Alexander demonstrated exceptional scientific leadership in over 15 years of experience in the biotechnology and pharmaceutical industries, where he has acquired a profound background in antibody engineering, drug discovery, development, and translational research. Before joining OncoOne, he was a Manager of R&D in Oncology Research at Shire where he led projects on antibodies and antibody-drug conjugates targeting oncological and hematologic disorders. Prior to that, he served in various positions with increasing levels of responsibility at Baxter BioScience and its successor, Baxalta, where Alexander significantly contributed to the development of the first generation of anti-oxMIF antibody, imalumab, supporting the progression from discovery through Phase II studies in various capacities. Alexander earned his PhD in biotechnology through an industry collaboration with Baxter BioScience and Baxalta from the University of Natural Resources and Life Sciences (BOKU) in Vienna.
Christine Landlinger-Schubert, PhD
Vice President Preclinical and Translational R&D
Christine Landlinger-Schubert, PhD
Vice President Preclinical and Translational R&D
Christine Landlinger-Schubert serves as Vice President of Preclinical and Translational R&D and leads the Inflammation program ON104 at OncoOne. She joined the company in 2021, bringing with her nearly 15 years of experience in drug discovery and non-clinical development in the biotech industry. At OncoOne, Christine has consistently showcased her exceptional leadership skills and has progressively taking on significant roles within the company. Before joining the company, Christine served as the Director of Lysins at PhagoMed, where she played a pivotal role in the development of pharmaceuticals to combat bacterial infections. In this role, she was instrumental in the European Union Institute of Innovation and Technology Health’s Goldtrack program, which ultimately led to the acquisition of PhagoMed by BioNTech. Prior to that, Christine served in various positions with increasing levels of responsibility at AFFiRiS, where she led preclinical activities for the development of active immunotherapies. Christine received her PhD in Life Science from the University of Vienna and conducted postdoctoral research at the Institute of Medical Biochemistry and the Children’s Cancer Research Institute in Vienna
Friedmund Bachmann
Vice President CMC
Friedmund Bachmann
Vice President CMC
Friedmund Bachmann serves as Vice President CMC and project lead for the Oncology program ON203 at OncoOne. With a rich experience spanning over two decades, Friedmund brings exceptional expertise in steering CMC programs across the entire product life cycle, showcasing his deep comprehension of the value chain for biological products. He became a part of the OncoOne team in 2021, consistently demonstrating outstanding leadership skills and leveraging his extensive knowledge to enhance our CMC department. Prior to his current role, he held various positions with ascending levels of responsibility within Pharmaceutical Sciences, CMC development, and CMC operations. His track record includes successful leadership of CMC programs encompassing the complete life cycle, spanning early-stage, late-stage, and commercial development for vaccines and products within oncology, hematology, and inflammatory diseases at prominent companies such as Baxter, Baxalta, Shire, and Takeda.
Maria Reitzinger, BA
Head of Finance and Administration
Maria Reitzinger, BA
Head of Finance and Administration
Maria Reitzinger serves as Head of Finance and Administration at OncoOne. Her extensive experience and background in cultural management bring a wealth of organizational and financial knowledge to our team. Since joining OncoOne in June 2020, Maria has continually expanded her responsibilities within the company, showcasing her adaptability and dedication. Prior to joining OncoOne, she served as the managing director of a prominent theater, where she was responsible for organizing festivals, concerts, and tourist events, demonstrating her expertise in responsible financial planning and effective project management. Maria holds a BA in Finance, Accounting, and Taxation from the University of Applied Sciences for Management & Communication.
Scientific Advisory Board
Prof. Michael Freissmuth, MD
Medical University Vienna, AT
Prof. Michael Freissmuth, MD
Director at Centre of Physiology & Pharmacology at Medical University Vienna
Dr. Freissmuth is the Director of the Center of Physiology & Pharmacology as well as the Chairman of the Institute of Pharmacology at the Medical University in Vienna. He was appointed Professor of Pharmacology in 1995 and received many awards, including the Novartis Award for Medicine. Dr. Freissmuth is a member of numerous editorial boards and serves on several review panels and scientific advisory boards. His most recent appointments include positions on international panels such as the Scientific Advisory Board of the Institut Cochin de Génétique Moléculaire in Paris and of the Engelhorn Foundation for Life Sciences. He is also a member of the supervisory board of Boehringer Ingelheim Austria. Dr. Freissmuth is an inaugural member of OncoOne’s scientific advisory board, where he continues to support the development of the company’s pipeline of biotherapeutics.
Prof. Dirk Jäger, MD
National Center for Tumor Diseases (NCT) Heidelberg, DE
Prof. Dirk Jäger, MD
Managing Director National Center for Tumor Diseases (NCT) Heidelberg
Dr. Jäger is Managing Director of the National Center for Tumor Diseases (NCT) Heidelberg and Medical Director of the Medical Oncology Department at Heidelberg University Hospital, where he is responsible for the clinical research area representing all oncological departments. The main focus of his department is the translation of innovative treatment options into early clinical trials. Since 2005, Dr. Jäger has been head of the research laboratory for tumor immunology at the NCT and focuses on cancer immunotherapy. He also leads the Clinical Cooperation Unit of Applied Tumor Immunity and has received the Investigator Award from the Cancer Research Institute in New York.
Prof. em. Florian Rüker, PhD
University of Natural Resources and Life Sciences, AT
Prof. em. Florian Rüker, PhD
Former Head of the Department of Biotechnology at the University of Natural Resources and Life Sciences Vienna
Dr. Florian Rüker is an Associate Professor and was Deputy Head of the Department of Biotechnology and Head of the Institute of Molecular Biotechnology at the University of Natural Resources and Life Sciences, Vienna (BOKU), encompassing a team of more than 230. He is a co-founder of F-star and co-inventor of F-star’s core Modular Antibody Technology, which allows for the generation of antigen-binding sites in constant domains of immunoglobulins. Dr. Rüker serves F-star as a Scientific Advisor. He also founded the Christian Doppler Laboratory (CD-Lab) for Antibody Engineering at BOKU, where he acted as co-head. Subsequently, he supported the establishment of the CD-Lab for Innovative Immunotherapeutics in collaboration with F-star and Merck KGaA, where he acts as Scientific Advisor.
Prof. Seamas Donnelly, MD
Trinity College Dublin, IRE
Prof. Seamas Donnelly, MD
Professor & Head of Medicine at the Trinity College Dublin and Hon. Professor in Translational Medicine of the University of Edinburgh
Dr. Seamas Donnelly is a Professor of Medicine at Trinity College Dublin. He is a global leader in translational medicine with a research focus on the development of novel compounds as anti-inflammatory/anti-cancer therapies. He has authored many MIF-focused publications in renowned peer-reviewed journals, including Nature Medicine and Molecular Medicine. Dr. Donnelly’s research epitomizes classical bench to bedside on an international scale, and, in recognition of this, has been awarded an Honorary Professorship in Translational Medicine by the University of Edinburgh. He is the current President of the Association of Physicians of Great Britain & Ireland, the leading academic medical association in the UK and Ireland. Dr. Donnelly is also the lead Trinity PI of Health Innovation Hub Ireland and has been a member of OncoOne’s scientific advisory board since 2022.
Prof. Jennifer Guerriero, PhD
Harvard Medical School, US
Prof. Jennifer Guerriero, PhD
Assistant Professor, Harvard Medical School and Director of the Breast Tumor lmmunology Laboratory at the Dana Farber Cancer Institute.
Dr. Jennifer Guerriero is an Assistant Professor of Surgery at Harvard Medical School and Lead Investigator at Brigham and Women’s Hospital, Division of Breast Surgery, Department of Surgery. She also serves as the Director of the Breast Tumor Immunology Laboratory at the Dana-Farber Cancer Institute. Dr. Guerriero’s research interests include harnessing the anti-tumor potential of tumor-associated macrophages for cancer immunotherapy in breast cancer. Her group studies the role of tumor associated macrophages both in promoting tumorigenesis as well as how to harness macrophages for cancer therapy. The major goals of Dr. Guerriero’s work are to elucidate the molecular and functional regulation of tumor macrophage phenotype and subsets, identify how tumor macrophages inhibit T cell function and limit the effectiveness of immunotherapy and identify novel strategies to target macrophages therapeutically. Dr. Guerriero completed her postdoctoral training at Dana-Farber Cancer Institute where she investigated the role of tumor macrophages in breast cancer and identified novel mechanisms to target pro-tumor macrophages to an anti-tumor phenotype to induce tumor regression. Dr. Guerriero also serves on the board for the Society for Immunotherapy of Cancer.
Prof. Robert A. Mitchell, MD
University of Louisville, US
Prof. Robert A. Mitchell, MD
Professor in the Department of Surgery and a member of the Division of lmmunotherapy at the University of Louisville.
Dr. Robert Mitchell is a tenured Professor in the Department of Surgery and a member of the Division of Immunotherapy at the University of Louisville. He has joint/associate appointments in the Departments of Microbiology & Immunology and Biochemistry & Molecular Genetics. His research is concentrated on the study of immune tolerance in tumor biology. Specifically, his work focuses on the macrophage migration inhibitory factor (MIF) family of cytokines and their independent and coordinated influences on myeloid lineage-dependent T cell suppressive mechanisms which govern tumor-associated immune evasion and subsequent disease progression. He and his laboratory have developed numerous patented pharmaceutical agents that are designed to treat malignant and nonmalignant diseases and they are currently evaluating whether these compounds have a specific role in governing MIF-dependent mitochondrial homeostasis that dictates myeloid cell immune suppression.
Clinical Advisory Board
Prof. Michael Freissmuth, MD
Medical University Vienna, AT
Prof. Michael Freissmith, MD
Director at Centre of Physiology & Pharmacology at Medical University Vienna
Dr. Freissmuth is the Director of the Center of Physiology & Pharmacology as well as the Chairman of the Institute of Pharmacology at the Medical University in Vienna. He was appointed Professor of Pharmacology in 1995 and received many awards, including the Novartis Award for Medicine. Dr. Freissmuth is a member of numerous editorial boards and serves on several review panels and scientific advisory boards. His most recent appointments include positions on international panels such as the Scientific Advisory Board of the Institut Cochin de Génétique Moléculaire in Paris and of the Engelhorn Foundation for Life Sciences. He is also a member of the supervisory board of Boehringer Ingelheim Austria. Dr. Freissmuth is an inaugural member of OncoOne’s scientific advisory board, where he continues to support the development of the company’s pipeline of biotherapeutics.
Prof. Seamas Donnelly, MD
Trinity College Dublin, IRE
Prof. Seamas Donnelly, MD
Professor & Head of Medicine at the Trinity College Dublin and Hon. Professor in Translational Medicine of the University of Edinburgh
Dr. Seamas Donnelly is a Professor of Medicine at Trinity College Dublin. He is a global leader in translational medicine with a research focus on the development of novel compounds as anti-inflammatory/anti-cancer therapies. He has authored many MIF-focused publications in renowned peer-reviewed journals, including Nature Medicine and Molecular Medicine. Dr. Donnelly’s research epitomizes classical bench to bedside on an international scale, and, in recognition of this, has been awarded an Honorary Professorship in Translational Medicine by the University of Edinburgh. He is the current President of the Association of Physicians of Great Britain & Ireland, the leading academic medical association in the UK and Ireland. Dr. Donnelly is also the lead Trinity PI of Health Innovation Hub Ireland and has been a member of OncoOne’s scientific advisory board since 2022.
Prof. Richard Bucala, MD, PhD
Yale School of Medicine, US
Richard Bucala, MD, PhD
Chief of Rheumatology, Allergy & Immunology at the Yale Institute for Global Health and the Waldemar Von Zedtwitz Endowed Professor of Medicine, Pathology, Epidemiology, & Public Health at the Yale School of Medicine
Dr. Bucala is renowned in MIF research and is recognized for discovering MIF's receptor CD74 as well as elucidating MIF's critical role in regulating glucocorticoid immunosuppression. He is an attending physician in the Yale New Haven Health System and is the past Editor-in-Chief of Arthritis & Rheumatology. Dr. Bucala was elected to the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP), in addition to having served on an advisory board for the United Nations and various other U.S. federal, academic, and pharmaceutical organizations.
Prof. Daniel Aletaha, MD
Medical University Vienna, AT
Daniel Aletaha, MD
Professor and Head of the Clinical Department of Rheumatology at the Medical University of Vienna.
Dr. Aletaha was appointed as an Honorary Member of the European Alliance of Associations for Rheumatology (EULAR) in 2016, and in 2023, he was elected as its president. His research focuses on arthritis and other inflammatory rheumatic diseases, precision medicine, and the management of complex diseases. He has experience in the areas of novel therapies and treatment strategies, diagnosis, prognosis, outcomes, and biomarkers. He currently holds over 350 indexed publications.
OncoOne Assembles a Team With the Perfect Blend of Experience, Precisely When It's Needed
The leadership team at OncoOne comprises seasoned professionals with decades of collective expertise spanning all phases of discovery and development. Their extensive R&D expertise, coupled with firsthand experience guiding novel therapies successfully through regulatory pathways, paves the way for precision medicines aimed at effectively improving patient outcomes and quality of life.
Leadership Team
Randolf Kerschbaumer, PhD
Co-Founder & Chief Executive Officer
Randolf Kerschbaumer, PhD
Co-Founder & Chief Executive Officer
Dr. Randolf Kerschbaumer, CEO and Co-Founder of OncoOne, brings over 25 years of experience from academia and big pharma R&D to the company. His comprehensive understanding of the drug development process, from early screening through to clinical trials, has been pivotal in shaping OncoOne's success. Under his leadership, OncoOne has expanded its reach globally and established a subsidiary in the USA. Randolf's intellectual curiosity, passion for science, and entrepreneurial drive allow him to effectively merge scientific innovation with strategic business planning. Before founding OncoOne, Randolf held several senior-level positions in R&D, focusing on therapeutics for cancer, inflammation, and hematologic disorders. He started his professional career at Baxter BioScience, progressing to senior leadership roles such as Head of Antibody Technology at Baxalta and Head of Oncology Research at Shire. His work has significantly contributed to the discovery and progression of antibody-based drug modalities with therapeutic potential from concept to Phase II clinical studies. Randolf earned his PhD in Biotechnology from the Vienna University of Natural Resources and Life Sciences (BOKU).
Michael Thiele, PhD
Co-Founder & Chief Scientific Officer
Michael Thiele, PhD
Co-Founder & Chief Scientific Officer
Michael, Co-Founder and Chief Scientific Officer (CSO) at OncoOne, has over two decades of expertise in immunology, tumor biology, biomarker discovery, and the development of biologics. As the CSO, he leads the company's strategic direction and drives the innovative PreTarg-it® platform, which aims for targeted delivery of therapies directly to tumor sites. Michael's profound knowledge of cell biology and his extensive global scientific connections enable him to establish and maintain strong partnerships with top experts in the field. Before establishing OncoOne, he led the Department of Cell Biology in Oncology Research at Shire. Earlier in his career, Michael held progressively senior roles at Baxter BioScience and its successor, Baxalta, collaborating with leading academics and industry leaders. Michael's significant contributions to medical science include recognizing oxMIF as a key therapeutic target, which marks a crucial advance in the creation of new therapies for autoimmune and chronic inflammatory conditions. Michael has been instrumental in advancing the first-generation anti-oxMIF antibody, imalumab, from early-stage research to phase II clinical trials. He obtained his PhD in Biology from the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, where he investigated tumor-promoting and pro-inflammatory properties of MIF.
Alexander Schinagl, PhD
Co-Founder & Chief Technology Officer
Alexander Schinagl, PhD
Co-Founder & Chief Technology Officer
Alexander Schinagl, Co-Founder and Chief Technology Officer at OncoOne, plays a pivotal role in the company's antibody design and engineering programs. In addition, he provides IP counsel to ensure robust patent protection. Alexander demonstrated exceptional scientific leadership in over 15 years of experience in the biotechnology and pharmaceutical industries, where he has acquired a profound background in antibody engineering, drug discovery, development, and translational research. Before joining OncoOne, he was a Manager of R&D in Oncology Research at Shire where he led projects on antibodies and antibody-drug conjugates targeting oncological and hematologic disorders. Prior to that, he served in various positions with increasing levels of responsibility at Baxter BioScience and its successor, Baxalta, where Alexander significantly contributed to the development of the first generation of anti-oxMIF antibody, imalumab, supporting the progression from discovery through Phase II studies in various capacities. Alexander earned his PhD in biotechnology through an industry collaboration with Baxter BioScience and Baxalta from the University of Natural Resources and Life Sciences (BOKU) in Vienna.
Maria Reitzinger, BA
Head of Finance and Administration
Maria Reitzinger, BA
Head of Finance and Administration
Maria Reitzinger serves as Head of Finance and Administration at OncoOne. Her extensive experience and background in cultural management bring a wealth of organizational and financial knowledge to our team. Since joining OncoOne in June 2020, Maria has continually expanded her responsibilities within the company, showcasing her adaptability and dedication. Prior to joining OncoOne, she served as the managing director of a prominent theater, where she was responsible for organizing festivals, concerts, and tourist events, demonstrating her expertise in responsible financial planning and effective project management. Maria holds a BA in Finance, Accounting, and Taxation from the University of Applied Sciences for Management & Communication.
Christine Landlinger-Schubert, PhD
Vice President Preclinical and Translational R&D
Christine Landlinger-Schubert, PhD
Vice President Preclinical and Translational R&D
Christine Landlinger-Schubert serves as Vice President of Preclinical and Translational R&D and leads the Inflammation program ON104 at OncoOne. She joined the company in 2021, bringing with her nearly 15 years of experience in drug discovery and non-clinical development in the biotech industry. At OncoOne, Christine has consistently showcased her exceptional leadership skills and has progressively taking on significant roles within the company. Before joining the company, Christine served as the Director of Lysins at PhagoMed, where she played a pivotal role in the development of pharmaceuticals to combat bacterial infections. In this role, she was instrumental in the European Union Institute of Innovation and Technology Health’s Goldtrack program, which ultimately led to the acquisition of PhagoMed by BioNTech. Prior to that, Christine served in various positions with increasing levels of responsibility at AFFiRiS, where she led preclinical activities for the development of active immunotherapies. Christine received her PhD in Life Science from the University of Vienna and conducted postdoctoral research at the Institute of Medical Biochemistry and the Children’s Cancer Research Institute in Vienna
Friedmund Bachmann
Vice President CMC
Friedmund Bachmann
Vice President CMC
Friedmund Bachmann serves as Vice President CMC and project lead for the Oncology program ON203 at OncoOne. With a rich experience spanning over two decades, Friedmund brings exceptional expertise in steering CMC programs across the entire product life cycle, showcasing his deep comprehension of the value chain for biological products. He became a part of the OncoOne team in 2021, consistently demonstrating outstanding leadership skills and leveraging his extensive knowledge to enhance our CMC department. Prior to his current role, he held various positions with ascending levels of responsibility within Pharmaceutical Sciences, CMC development, and CMC operations. His track record includes successful leadership of CMC programs encompassing the complete life cycle, spanning early-stage, late-stage, and commercial development for vaccines and products within oncology, hematology, and inflammatory diseases at prominent companies such as Baxter, Baxalta, Shire, and Takeda.
Scientific Advisory Board
Prof. Michael Freissmuth, MD
Medical University Vienna, AT
Prof. Michael Freissmuth, MD
Director at Centre of Physiology & Pharmacology at Medical University Vienna
Dr. Freissmuth is the Director of the Center of Physiology & Pharmacology as well as the Chairman of the Institute of Pharmacology at the Medical University in Vienna. He was appointed Professor of Pharmacology in 1995 and received many awards, including the Novartis Award for Medicine. Dr. Freissmuth is a member of numerous editorial boards and serves on several review panels and scientific advisory boards. His most recent appointments include positions on international panels such as the Scientific Advisory Board of the Institut Cochin de Génétique Moléculaire in Paris and of the Engelhorn Foundation for Life Sciences. He is also a member of the supervisory board of Boehringer Ingelheim Austria. Dr. Freissmuth is an inaugural member of OncoOne’s scientific advisory board, where he continues to support the development of the company’s pipeline of biotherapeutics.
Prof. Dirk Jäger, MD
National Center for Tumor Diseases (NCT) Heidelberg, DE
Prof. Dirk Jäger, MD
Managing Director National Center for Tumor Diseases (NCT) Heidelberg
Dr. Jäger is Managing Director of the National Center for Tumor Diseases (NCT) Heidelberg and Medical Director of the Medical Oncology Department at Heidelberg University Hospital, where he is responsible for the clinical research area representing all oncological departments. The main focus of his department is the translation of innovative treatment options into early clinical trials. Since 2005, Dr. Jäger has been head of the research laboratory for tumor immunology at the NCT and focuses on cancer immunotherapy. He also leads the Clinical Cooperation Unit of Applied Tumor Immunity and has received the Investigator Award from the Cancer Research Institute in New York.
Prof. em. Florian Rüker, PhD
University of Natural Resources and Life Sciences, AT
Prof. em. Florian Rüker, PhD
Former Head of the Department of Biotechnology at the University of Natural Resources and Life Sciences Vienna
Dr. Florian Rüker is an Associate Professor and was Deputy Head of the Department of Biotechnology and Head of the Institute of Molecular Biotechnology at the University of Natural Resources and Life Sciences, Vienna (BOKU), encompassing a team of more than 230. He is a co-founder of F-star and co-inventor of F-star’s core Modular Antibody Technology, which allows for the generation of antigen-binding sites in constant domains of immunoglobulins. Dr. Rüker serves F-star as a Scientific Advisor. He also founded the Christian Doppler Laboratory (CD-Lab) for Antibody Engineering at BOKU, where he acted as co-head. Subsequently, he supported the establishment of the CD-Lab for Innovative Immunotherapeutics in collaboration with F-star and Merck KGaA, where he acts as Scientific Advisor.
Prof. Seamas Donnelly, MD
Trinity College Dublin, IRE
Prof. Seamas Donnelly, MD
Professor & Head of Medicine at the Trinity College Dublin and Hon. Professor in Translational Medicine of the University of Edinburgh
Dr. Seamas Donnelly is a Professor of Medicine at Trinity College Dublin. He is a global leader in translational medicine with a research focus on the development of novel compounds as anti-inflammatory/anti-cancer therapies. He has authored many MIF-focused publications in renowned peer-reviewed journals, including Nature Medicine and Molecular Medicine. Dr. Donnelly’s research epitomizes classical bench to bedside on an international scale, and, in recognition of this, has been awarded an Honorary Professorship in Translational Medicine by the University of Edinburgh. He is the current President of the Association of Physicians of Great Britain & Ireland, the leading academic medical association in the UK and Ireland. Dr. Donnelly is also the lead Trinity PI of Health Innovation Hub Ireland and has been a member of OncoOne’s scientific advisory board since 2022.
Prof. Jennifer Guerriero, PhD
Harvard Medical School, US
Prof. Jennifer Guerriero, PhD
Assistant Professor, Harvard Medical School and Director of the Breast Tumor lmmunology Laboratory at the Dana Farber Cancer Institute.
Dr. Jennifer Guerriero is an Assistant Professor of Surgery at Harvard Medical School and Lead Investigator at Brigham and Women’s Hospital, Division of Breast Surgery, Department of Surgery. She also serves as the Director of the Breast Tumor Immunology Laboratory at the Dana-Farber Cancer Institute. Dr. Guerriero’s research interests include harnessing the anti-tumor potential of tumor-associated macrophages for cancer immunotherapy in breast cancer. Her group studies the role of tumor associated macrophages both in promoting tumorigenesis as well as how to harness macrophages for cancer therapy. The major goals of Dr. Guerriero’s work are to elucidate the molecular and functional regulation of tumor macrophage phenotype and subsets, identify how tumor macrophages inhibit T cell function and limit the effectiveness of immunotherapy and identify novel strategies to target macrophages therapeutically. Dr. Guerriero completed her postdoctoral training at Dana-Farber Cancer Institute where she investigated the role of tumor macrophages in breast cancer and identified novel mechanisms to target pro-tumor macrophages to an anti-tumor phenotype to induce tumor regression. Dr. Guerriero also serves on the board for the Society for Immunotherapy of Cancer.
Prof. Robert A. Mitchell, MD
University of Louisville, US
Prof. Robert A. Mitchell, MD
Professor in the Department of Surgery and a member of the Division of lmmunotherapy at the University of Louisville.
Dr. Robert Mitchell is a tenured Professor in the Department of Surgery and a member of the Division of Immunotherapy at the University of Louisville. He has joint/associate appointments in the Departments of Microbiology & Immunology and Biochemistry & Molecular Genetics. His research is concentrated on the study of immune tolerance in tumor biology. Specifically, his work focuses on the macrophage migration inhibitory factor (MIF) family of cytokines and their independent and coordinated influences on myeloid lineage-dependent T cell suppressive mechanisms which govern tumor-associated immune evasion and subsequent disease progression. He and his laboratory have developed numerous patented pharmaceutical agents that are designed to treat malignant and nonmalignant diseases and they are currently evaluating whether these compounds have a specific role in governing MIF-dependent mitochondrial homeostasis that dictates myeloid cell immune suppression.
Clinical Advisory Board
Prof. Michael Freissmuth, MD
Medical University Vienna, AT
Prof. Michael Freissmith, MD
Director at Centre of Physiology & Pharmacology at Medical University Vienna
Dr. Freissmuth is the Director of the Center of Physiology & Pharmacology as well as the Chairman of the Institute of Pharmacology at the Medical University in Vienna. He was appointed Professor of Pharmacology in 1995 and received many awards, including the Novartis Award for Medicine. Dr. Freissmuth is a member of numerous editorial boards and serves on several review panels and scientific advisory boards. His most recent appointments include positions on international panels such as the Scientific Advisory Board of the Institut Cochin de Génétique Moléculaire in Paris and of the Engelhorn Foundation for Life Sciences. He is also a member of the supervisory board of Boehringer Ingelheim Austria. Dr. Freissmuth is an inaugural member of OncoOne’s scientific advisory board, where he continues to support the development of the company’s pipeline of biotherapeutics.
Prof. Seamas Donnelly, MD
Trinity College Dublin, IRE
Prof. Seamas Donnelly, MD
Professor & Head of Medicine at the Trinity College Dublin and Hon. Professor in Translational Medicine of the University of Edinburgh
Dr. Seamas Donnelly is a Professor of Medicine at Trinity College Dublin. He is a global leader in translational medicine with a research focus on the development of novel compounds as anti-inflammatory/anti-cancer therapies. He has authored many MIF-focused publications in renowned peer-reviewed journals, including Nature Medicine and Molecular Medicine. Dr. Donnelly’s research epitomizes classical bench to bedside on an international scale, and, in recognition of this, has been awarded an Honorary Professorship in Translational Medicine by the University of Edinburgh. He is the current President of the Association of Physicians of Great Britain & Ireland, the leading academic medical association in the UK and Ireland. Dr. Donnelly is also the lead Trinity PI of Health Innovation Hub Ireland and has been a member of OncoOne’s scientific advisory board since 2022.
Prof. Richard Bucala, MD, PhD
Yale School of Medicine, US
Richard Bucala, MD, PhD
Chief of Rheumatology, Allergy & Immunology at the Yale Institute for Global Health and the Waldemar Von Zedtwitz Endowed Professor of Medicine, Pathology, Epidemiology, & Public Health at the Yale School of Medicine
Dr. Bucala is renowned in MIF research and is recognized for discovering MIF's receptor CD74 as well as elucidating MIF's critical role in regulating glucocorticoid immunosuppression. He is an attending physician in the Yale New Haven Health System and is the past Editor-in-Chief of Arthritis & Rheumatology. Dr. Bucala was elected to the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP), in addition to having served on an advisory board for the United Nations and various other U.S. federal, academic, and pharmaceutical organizations.
Prof. Daniel Aletaha, MD
Medical University Vienna, AT
Daniel Aletaha, MD
Professor and Head of the Clinical Department of Rheumatology at the Medical University of Vienna.
Dr. Aletaha was appointed as an Honorary Member of the European Alliance of Associations for Rheumatology (EULAR) in 2016, and in 2023, he was elected as its president. His research focuses on arthritis and other inflammatory rheumatic diseases, precision medicine, and the management of complex diseases. He has experience in the areas of novel therapies and treatment strategies, diagnosis, prognosis, outcomes, and biomarkers. He currently holds over 350 indexed publications.
Our team is highly committed to making a meaningful difference in people's lives through our innovative therapies.
